Administrators from KPMG have been appointed to three companies engaged in drug, alcohol and paternity testing.
Screensafe UK Limited, Trimega Laboratories Limited and Ingemino Testing Services Limited entered administration following a decline in the testing markets.
49 staff have been made redundant as a result of the insolvencies.
Paul Flint and Brian Green of KPMG were appointed as joint administrators to the companies on 7 April 2014.
The business and assets of Screensafe UK, an alcohol and drug testing firm based in Stafford, were sold out of administration to Synergy Health Laboratory Services Limited following the appointment of administrators.
A sale of Trimega Laboratories Limited and Ingemino Testing Services Limited, both based in Greater Manchester, could not be secured.
Trimega Laboratories provided legally defensible testing that supports critical decisions in child protection cases. Ingemino Testing Services operated the laboratory companies where the Screensafe and Trimega testing was conducted.
Flint, associate partner at KPMG and joint administrator, said: “The paternity testing market has declined as a result of recent changes to the legal aid system.
“Despite marketing the Trimega Laboratories and Ingemino Testing Services business as going concerns prior to our appointment, a buyer could not be found and unfortunately, a total of 49 redundancies have been made across these two businesses in Blackley.”